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DSD - Dangerous Substances Directive 67/548/EEC
CLP - Classification, labelling & packaging
GHS - Global Harmonised System
 CLP is the Regulation on classification, labelling and packaging of substances and mixtures. This Regulation aligns previous EU legislation on classification, labelling and packaging of chemicals to the GHS (Globally Harmonised System of Classification and Labelling of Chemicals). Its main objectives are to facilitate international trade in chemicals and to maintain the existing level of protection of human health and environment. The GHS is a United Nations system to identify hazardous chemicals and to inform users about these hazards through standard symbols and phrases on the packaging labels and through safety data sheets (SDS).

The CLP Regulation was published in the Official Journal 31 December 2008 and entered into force on 20 January 2009. According to the Regulation, the deadline for substance classification according to the new rules will be 1 December 2010. For mixtures, the deadline will be 1 June 2015. The CLP Regulation will ultimately replace the current rules on classification, labelling and packaging of substances (Directive 67/548/EEC) and preparations (Directive 1999/45/EC) after this transitional period.


You can find an example as follows.

Formaldehyde (CH2O)

Formula: CH2O
Molecular Weight: 30.026 g/mol
Name formaldehyde
CAS-RN 50-00-0
EG-Index: 605-001-00-5 (96/54/EC)
EINECS: 200-001-8 (EINECS)

Hazard Information (Dangerous Substances Directive 67/548/EEC)

Hazard symbol


R23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
R34 Causes burns.
R40 Possible risks of irreversible effects.
R43 May cause sensitization by skin contact.



S1/2 Keep locked up and out of the reach of children.
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S51 Use only in well-ventilated areas.


Signal Word Danger EC/1272/2008
Hazard Statements
H351 Suspected of causing cancer .
H331 Toxic if inhaled.
H311 Toxic in contact with skin.
H301 Toxic if swallowed.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
Precautionary Statements
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do no eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301+P330+P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P302+P352 IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P311 Call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see ... on this label).
P322 Specific measures (see ... on this label).
P330 Rinse mouth.
P333+P313 If skin irritation or rash occurs: Get medical advice/attention.
P361 Remove/Take off immediately all contaminated clothing.
P363 Wash contaminated clothing before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to ...
Classification Carc. 2
Acute Tox. 3 *
Acute Tox. 3 *
Acute Tox. 3 *
Skin Corr. 1B
Skin Sens. 1
EC-Reference 605-001-00-5
Disclaimer: The information on these webpages has been developed to provide basic information to stakeholders regarding CLP/GHS. Please note that this information is not a substitute for the relevant legislation and that only the text of the CLP Regulation and any related measures are authentic.